1. The causative agent of tetanus is
a. Clostridium botulinum
b. Cl. tetani
c. Cl. welchii
d. Cl. perfringens
Answer:b. Cl. tetani
2. The mode of spread of tetanus neurotoxin from blood to brain is
a. Via lymphatics
b. Arterial blood
c. Cranial nerves
d. None of these
Answer:c. Cranial nerves
3. Tetanus is caused by spread of
a. Exotoxin in sympathetic system
b. Exotoxin in parasympathetic system
c. Endotoxin in sympathetic system
d. Endotoxin in parasympathetic system
Answer:a. Exotoxin in sympathetic system
4. The first symptom of tetanus is
a. Lock jaw
b. Trismus
c. Anorexia
d. Dysphagia
Answer:b. Trismus
5. Of which clostridia, the neurotoxin is most powerful?
a. Cl. tetani
b. Cl. welchii
c. Cl. botulism
d. Cl. septicum
Answer:c. Cl. botulism
6. Toxin produced by C. botulism is
a. Botulin
b. Tetanospasmin
c. Tetanolysin
d. Cholaragen
Answer:a. Botulin
7. “Toxic shock syndrome” is caused by the toxin of
a. Staphylococcus aureus
b. Streptococcus pyogen
c. Vibrio cholerae
d. Candida
Answer:a. Staphylococcus aureus
8. Causative agent of syphilis
a. T. pallidum
b. T. pertenue
c. T. carateum
d. T. endemicum
Answer:a. T. pallidum
9. Spirochaetes are sensitive to
a. Penicillin
b. Chloramphenicols
c. Erythromycin
d. Tetracycline
Answer:b. Chloramphenicols
10. Specific test for syphilis is
a. VDRL test
b. ELISA
c. FTA
d. None of these
Answer:a. VDRL test
11. VDRL test is a
a. Agglutination test
b. Slide flocculation test
c. Precipitation test
d. None of these
Answer:b. Slide flocculation test
12. The following characters are true about Neisseria gonorrhoeae except
a. Gram-negative, aerobic bacteria
b. Non-motile diplococci
c. Oxidase positive organisms
d. Air borne infection
Answer:d. Air borne infection
13. Gonorrhoea is
a. Air borne disease
b. Water borne disease
c. Sexually transmitted venereal disease
d. Both a and c
Answer:c. Sexually transmitted venereal disease
14. Bartholin cyst is caused by
a. Candida
b. Streptococcus
c. Staphylococcus
d. Gonococcus
Answer:d. Gonococcus
15. Neisseria gonorrhoeae causes
a. Urethritis
b. Conjunctivitis
c. Arthritis
d. All of the above
Answer:d. All of the above
16. Virulence in gonococcus is due to
a. Pili
b. Cell membrane
c. Its cellular location
d. Cyclic enzymes
Answer:a. Pili
17. Japanese encephalitis is caused by
a. Toga Viruses
b. Arboviruses
c. Paramyxoviruses
d. Orthomyxoviruses
Answer:b. Arboviruses
18. In India, Japanese b encephalitis was first isolated from the mosquitoes of the
a. Culex tritaeniorhynchus
b. Culex annulirostris
c. Culex vishnui
d. None of these
Answer:c. Culex vishnui
19. Dengue virus is transmitted from man to man by the
a. Sand fly
b. Ticks
c. Aedes aegypti
d. Culex
Answer:c. Aedes aegypti
20. Yellow fever is caused by
a. Bunya virus
b. Calicivirus
c. Arbovirus
d. None of these
Answer:c. Arbovirus
21. Vector for leishmaniasis is
a. Tick
b. Mite
c. Sand fly
d. Tsetse fly
Answer:c. Sand fly
22. Splenomegaly is an important manifestation of
a. Kala-agar
b. Typhoid
c. Malaria
d. All of these
Answer:d. All of these
23. Which of the following is most severely affected in Kala-azar?
a. Liver
b. Spleen
c. Adrenal gland
d. Bone marrow
Answer:b. Spleen
24. In India, malaria most often spreads by
a. Anopheles culicifacies
b. Anopheles fluviatilis
c. Anopheles stephensi
d. Anopheles minimus
Answer:a. Anopheles culicifacies
25. Man is an intermediate host for
a. Guinea Worm
b. Filaria
c. Malaria
d. Kala-azar
Answer:c. Malaria
26. Which of the following preferably infects reticulocytes?
a. P. ovale
b. P.vivax
c. P.falciparum
d. P.malaria
Answer:b. P.vivax
27. In which type of material are parasites in the exoerythrocytic stage absent?
a. P.ovale
b. P.vivax
c. P.falciparum
d. P. malariae
Answer:c. P.falciparum
28. In falciparum malaria, all of the following stages are seen except
a. Ring stage
b. Schizont
c. Gametocyte
d. None of these
Answer:b. Schizont
29. Sporozoite vaccine in malaria has
a. Induces antibodies
b. Prevents only asexual forms with reproduction
c. No effects on clinical illness
d. None of the above
Answer:a. Induces antibodies
30. Growing trophozoites and schizonts are not seen in the peripheral blood in malaria due to
a. P. falciparum
b. P.vivax
c. P.ovale
d. P. malaria
Answer:a. P. falciparum
31. Thin blood smear for malaria is used to identify
a. Plasmodium
b. Gametocytes
c. Type of parasite
d. Schizont
Answer:c. Type of parasite
32. The radical treatment of malaria is to half
a. Gametocyte
b. Exo-erythrocytic phase
c. Erythrocytic phase
d. All of these
Answer:c. Erythrocytic phase
33. Symptoms of acute aflatoxicosis
a. Osteogenic sarcoma
b. Lymphatic leukemia
c. Malaise & Anorexia
d. Both a and b
Answer:d. Both a and b
34. Most important Penicillium toxins are
a. Citrinin
b. Patulin
c. Penicillic acid
d. All of the above
Answer:d. All of the above
35. Penicillic acid is produced by
a. A. ochraceus
b. P. puberulum
c. Both a and b
d. None of the above
Answer:c. Both a and b
36. Fungi producing mycelium are called
a. Moulds
b. Filamentous fungi
c. Both a and b
d. Yeasts
Answer:a. Moulds
37. Candidiasis is caused by
a. Candida albicans
b. Aspergillus spp.
c. E. floccosum
d. M. audouinii
Answer:a. Candida albicans
38. Candida albicans is capable to form
a. Single cells
b. Pseudomonas
c. Multicellular forms
d. None of these
Answer:b. Pseudomonas
39. Aspergillus fumigatus can infect
a. A. niger
b. A. fumigatus
c. A. flavus
d. A. oryzae
Answer:d. A. oryzae
40. A.fumigates can produce
a. Endotoxins
b. Exotoxins
c. Enterotoxins
d. None of these
Answer:a. Endotoxins
41. The drug of choice for dermal, oral and vaginal candidiasis is
a. Griseofulvin
b. Amphotericin B
c. Gentian violet
d. Nystatin
Answer:c. Gentian violet
42. The following Penicillium species are pathogenic except
a. P. commune
b. P. bicolor
c. P. glaucum
d. P.notatum
Answer:d. P.notatum
43. Tinea versicolor is caused by
a. Candida albicans
b. Malassezia furfur
c. Aspergillus niger
d. None of these
Answer:b. Malassezia furfur
44. Causative agent of Tinea nigra
a. Malassezia furfur
b. Exophiala werneckii
c. Candida albicans
d. Aspergillus flavus
Answer:b. Exophiala werneckii
45. Causative agent of African histoplasmosis
a. Histoplasma capsulatum
b. Histoplasma duboisii
c. Aspergillus niger
d. Aspergillus flavus
Answer:b. Histoplasma duboisii
46. Sun ray fungus is
a. Actinomyces israelii
b. Chromoblastomycosis
c. Streptomyces griseus
d. Cryptococcosis
Answer:a. Actinomyces israelii
47. Which agent in addition to a colony inhibits its growth and on removal the colony regrows?
a. Bacteriostatic
b. Bactericidal
c. Antibiotic
d. Antiseptic
Answer:a. Bacteriostatic
48. Griseofulvin is obtained from
a. Penicillium notatum
b. Streptomyces griseus
c. Penicillium griseofulvin
d. None of these
Answer:c. Penicillium griseofulvin
49. β-lactam ring is present in
a. Erythromycin
b. Penicillin
c. Tetracycline
d. Chloramphenicol
Answer:b. Penicillin
50. All of the following drugs act on cell membrane, except
a. Novobiocin
b. Nystatin
c. Chloromycetin
d. Colicins
Answer:d. Colicins
